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KMID : 0043320030260110898
Archives of Pharmacal Research
2003 Volume.26 No. 11 p.898 ~ p.901
Diterpenoids from the Stem Barks of Croton robustus
Nattya-Ngamrojnavanich

Sorasaree-Tonseiengsom
Preecha-Lertpratchya
Sophon-Roengsumran
Songchan-Puthong
Amorn Petsom
Abstract
Three compounds were isolated from the stem barks of Croton robustus. Their structures were elucidated as trachyloban-19-oic, acid, trachyloban-19-ol and poilaneic acid by spectroscopic analysis. Among them, trachyloban-19-ol and methyl trachyloban-19-oate exhibited weak cytotoxic activity against gastric carcinoma and colon carcinoma with of 9.2, 9.6 and 8.3, , respectively.
KEYWORD
Croton robustus, Trachyloban-19-oic acid, Trachyloban-19-ol, Poilaneic acid, Cytotoxic activity
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