KMID : 0043320030260110898
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Archives of Pharmacal Research 2003 Volume.26 No. 11 p.898 ~ p.901
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Diterpenoids from the Stem Barks of Croton robustus
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Nattya-Ngamrojnavanich
Sorasaree-Tonseiengsom Preecha-Lertpratchya Sophon-Roengsumran Songchan-Puthong Amorn Petsom
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Abstract
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Three compounds were isolated from the stem barks of Croton robustus. Their structures were elucidated as trachyloban-19-oic, acid, trachyloban-19-ol and poilaneic acid by spectroscopic analysis. Among them, trachyloban-19-ol and methyl trachyloban-19-oate exhibited weak cytotoxic activity against gastric carcinoma and colon carcinoma with of 9.2, 9.6 and 8.3, , respectively.
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KEYWORD
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Croton robustus, Trachyloban-19-oic acid, Trachyloban-19-ol, Poilaneic acid, Cytotoxic activity
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